Conditions

What Happens if I Don’t Give My Dog Heartworm Medication?

Owner standing outside with her dog

Skipping heartworm medication can put your dog at serious risk, as even a single mosquito bite can lead to infection that damages the heart, lungs, and blood vessels over time. Without prevention, dogs may develop symptoms such as coughing, fatigue, respiratory distress, and even life-threatening complications requiring intensive treatment and supportive care. Consistent monthly prevention and early testing are the best ways to protect your dog and ensure they live a healthy, comfortable life.

dog owner and dog talking to a vet about a cough

Understanding Heartworm Disease


Heartworm disease is a serious and potentially life-threatening condition caused by parasitic worms transmitted through mosquito bites. Once infected, the worms travel through the bloodstream and settle in the heart, lungs, and nearby blood vessels, where they grow, multiply, and cause significant damage. Even indoor dogs are at risk, as it only takes one infected mosquito to transmit heartworm disease. This is why consistent heartworm prevention is one of the most important steps you can take to protect your dog’s long-term health.

What Happens When Heartworm Prevention Is Skipped


When heartworm prevention is missed, even for a short period, immature heartworms can begin developing inside your dog’s body, eventually reaching the heart, lungs, and blood vessels. As these worms grow and multiply, they cause inflammation, strain on the heart, and damage to lung tissue, even before visible symptoms appear. Early signs of infection are often subtle and easy to overlook, making regular prevention and yearly testing especially important.


Early signs of heartworm infection may include:

  • Mild or persistent cough
  • Fatigue, especially after light activity
  • Decreased endurance or reluctance to exercise
  • Gradual weight loss or reduced appetite

As the infection progresses without treatment, these symptoms can worsen and lead to more serious heart and lung complications.

Symptoms of Moderate to Severe Infection


As heartworms multiply and grow, they begin to obstruct blood flow and damage the heart, lungs, and surrounding blood vessels. This leads to inflammation and scarring of lung tissue, making it harder for your dog to breathe and deliver oxygen throughout the body. Breathing difficulties can come on gradually or suddenly, and witnessing these episodes can be frightening for both pets and their families.


Signs of respiratory distress may include:

  • Rapid, shallow, or labored breathing
  • Frequent or persistent coughing
  • Blue or pale gums (indicating low oxygen levels)
  • Episodes of collapse or fainting

As the disease advances, additional symptoms may appear due to strain on the heart and circulatory system. These indicators suggest more serious organ involvement and require urgent veterinary care.

Other signs of advanced heartworm disease include:

  • Swollen belly due to fluid buildup (ascites)
  • Extreme lethargy or weakness
  • Fainting or collapse during mild activity
  • Caval Syndrome, a life-threatening form of heartworm disease that requires emergency treatment

Left untreated, heartworm disease can lead to permanent damage or even be fatal, which is why early detection and prompt care are essential.

Treatment and Supportive Care


Treating heartworm disease involves a series of veterinary-administered medications designed to safely eliminate the worms, along with strict rest to prevent dangerous complications. Because dying heartworms can cause inflammation or block major blood vessels, treatment must be carefully supervised, and dogs need limited activity while their body heals. In more advanced cases, supportive care can help manage symptoms and improve comfort, especially when the heart and lungs are affected.


Supportive at-home care may include:

  • Monitoring your dog’s breathing, energy levels, and comfort
  • Using supplemental at-home oxygen therapy to improve oxygen levels and reduce breathing effort during recovery
  • Creating a calming, low-stress environment to help reduce strain on the heart and lungs

With proper treatment and attentive home care, many dogs can recover and return to a healthy, active life.

Can my dog really get heartworms if they live mostly indoors or only go outside for a short time?

Yes, because heartworm disease is spread by mosquitoes, and it only takes one infected mosquito to transmit the disease, even to dogs that spend most of their time indoors or have limited outdoor exposure.

What are the symptoms of heartworm disease, and how can I tell if my dog might have it?

Early symptoms are often subtle and may include coughing, fatigue, or reduced endurance, but as the disease progresses, dogs may develop difficulty breathing, weight loss, or even signs of heart failure, making early testing essential.

Is heartworm medication really necessary year-round, and is it safe for my dog?

Year-round prevention is strongly recommended because mosquitoes can survive in many climates for most of the year, and modern heartworm medications are safe, effective, and much more affordable than treating an infection.

Prevention and Long-Term Care


Heartworm prevention is not only safer and easier than treatment. It’s also significantly more affordable and far less stressful for both you and your dog. Preventative medications, available as oral chewable treats, topical applications, or long-lasting injections, work by eliminating immature heartworms before they can cause damage. Year-round prevention is essential, even for indoor dogs, since one mosquito bite is all it takes to transmit the disease. After treatment or any missed prevention, follow-up testing helps ensure your dog remains healthy and heartworm-free.

Final Thoughts


Heartworm disease is a serious condition, but the good news is that it’s almost entirely preventable with consistent care and protection. Skipping prevention can put your dog at risk for heart and lung complications, including respiratory emergencies that may require specialized supportive care. By staying on top of prevention, scheduling regular testing, and acting quickly if symptoms appear, you can help ensure your dog enjoys a comfortable, healthy life for years to come.

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